美国文理科学院聘请中国文化大学两名研究员

剑桥,质量。今年将有7名哥伦比亚大学教员入选美国艺术与科学院，其中包括哥伦比亚大学医学中心的两名研究人员:癌症研究所所长麦克斯韦尔·e·戈特斯曼(Maxwell E. Gottesman)和遗传学与发育教授罗德尼·j·罗斯坦(Rodney J. Rothstein)。“我很荣幸能够入选，并感谢我在该领域的同事们以这种方式认可我，”罗斯坦博士在得知他的入选后说。罗斯坦博士因阐明识别和修复DNA损伤的基本生物学过程而被选中。罗斯坦博士也一直在研究一种特殊类型的细胞分裂，这种细胞分裂在酵母中也存在于成体干细胞中。通过使用出芽酵母作为实验生物，罗斯坦博士等研究人员旨在找到更好的工具来识别隐藏在成体组织中的成体干细胞。Gottesman博士因其对大肠杆菌转录终止的研究而被选中。他已经证明翻译和转录是由NusG蛋白偶联的，不能终止转录会导致染色体断裂。如果不能修复这些断裂，可能会产生灾难性的后果，包括癌症。其他工作涉及DNA双链断裂修复机制以及修复与DNA甲基化之间的联系。 Dr. Gottesman and his colleagues have determined that PTPD1, the protein tyrosine phosphatase that activates Src, is up-regulated in bladder cancer. Other Columbians named to this year’s class are: Shou-Wu Zhang, professor of mathematics, Shree K. Nayar, co-director of the Columbia Vision and Graphics Center; T.C. Chang Professor, Computer Science, Mark Mazower, Ira D. Wallach Professor of World Order Studies; professor of history, James S. Shapiro, Larry Miller Professor of English, and Michael Scammell, biographer, translator and professor in the Department of Creative Writing. Since its founding in 1780 by John Adams, James Bowdoin, John Hancock, and other scholar-patriots, the Academy has elected leading “thinkers and doers” from each generation, including George Washington, Benjamin Franklin, Albert Einstein and Winston Churchill. The current membership includes more than 250 Nobel laureates and more than 60 Pulitzer Prize winners. For a full list of the 231st class of fellows, please see the official American Academy of Sciences announcement here. ### Columbia University Medical Center provides international leadership in basic, pre-clinical and clinical research, in medical and health sciences education, and in patient care. The medical center trains future leaders and includes the dedicated work of many physicians, scientists, public health professionals, dentists, and nurses at the College of Physicians and Surgeons, the Mailman School of Public Health, the College of Dental Medicine, the School of Nursing, the biomedical departments of the Graduate School of Arts and Sciences, and allied research centers and institutions. Established in 1767, Columbia’s College of Physicians and Surgeons was the first institution in the country to grant the M.D. degree and is now among the most selective medical schools in the country. Columbia University Medical Center is home to the most comprehensive medical research enterprise in New York City and State and one of the largest in the United States. Columbia University Medical Center is affiliated with NewYork-Presbyterian Hospital, the nation’s largest not-for-profit, non-sectarian hospital provider. For more information, please visitwww.cumc.columbia.edu．